Identification and Characterization of Four c-di-GMP-Metabolizing Enzymes from <i>Streptomyces ghanaensis</i> ATCC14672 Involved in the Regulation of Morphogenesis and Moenomycin A Biosynthesis

Diguanylate cyclases (DGCs) and phosphodiesterases (PDEs) are essential enzymes deputed to maintain the intracellular homeostasis of the second messenger cyclic dimeric (3′→5′) GMP (c-di-GMP). Recently, c-di-GMP has emerged as a crucial molecule for the streptomycetes life cycle, governing both morp...

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Bibliographic Details
Main Authors: Desirèe Nuzzo, Roman Makitrynskyy, Olga Tsypik, Andreas Bechthold
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/9/2/284