DeepNano: Deep recurrent neural networks for base calling in MinION nanopore reads.

The MinION device by Oxford Nanopore produces very long reads (reads over 100 kBp were reported); however it suffers from high sequencing error rate. We present an open-source DNA base caller based on deep recurrent neural networks and show that the accuracy of base calling is much dependent on the...

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Bibliographic Details
Main Authors: Vladimír Boža, Broňa Brejová, Tomáš Vinař
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5459436?pdf=render