Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans

Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans

In order to identify the molecular mechanisms that may contribute to the enhanced susceptibility to depression under serotonin transporter (SERT) dysfunction, we analyzed the expression of brain-derived neurotrophic factor (BDNF), a key player in neuronal plasticity, which is implicated in the etiol...

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Bibliographic Details
Main Authors: Raffaella Molteni, Annamaria Cattaneo, Francesca Calabrese, Flavia Macchi, Jocelien D.A. Olivier, Giorgio Racagni, Bart A. Ellenbroek, Massimo Gennarelli, Marco A. Riva
Format: Article
Language:English
Published: Elsevier 2010-03-01
Series:Neurobiology of Disease
Subjects:
Depression
Mutant rat
SERT
BDNF
Gene expression
Epigenetic mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109003696

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http://www.sciencedirect.com/science/article/pii/S0969996109003696

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