Effect of the KCa3.1 blocker, senicapoc, on cerebral edema and cardiovascular function after cardiac arrest — A randomized experimental rat study

Aim: Formation of cerebral edema and cardiovascular dysfunction may worsen brain injury following cardiac arrest. We hypothesized that administration of the intermediate calcium-activated potassium (KCa3.1) channel blocker, senicapoc, would reduce cerebral edema and augment mean arterial pressure in...

Full description

Bibliographic Details
Main Authors: Frederik Boe Hansen, Niels Secher, Thomas Mattson, Bo Løfgren, Ulf Simonsen, Asger Granfeldt
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Resuscitation Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666520421000369