Study on pharmacokinetics and tissue distribution of the isocorydine derivative (AICD) in rats by HPLC-DAD method

A simple and effective high-performance liquid chromatography with diode-array detection method coupled with a liquid-liquid extraction pretreatment has been developed for determining the pharmacokinetics and tissue distribution of a novel structurally modified derivative (8-acetamino-isocorydine) o...

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Bibliographic Details
Main Authors: Yali Chen, Qian Yan, Mei Zhong, Quanyi Zhao, Junxi Liu, Duolong Di, Jinxia Liu
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383515000568