Trichothecene Mycotoxins Inhibit Mitochondrial Translation—Implication for the Mechanism of Toxicity

Trichothecene Mycotoxins Inhibit Mitochondrial Translation—Implication for the Mechanism of Toxicity

Fusarium head blight (FHB) reduces crop yield and results in contamination of grains with trichothecene mycotoxins. We previously showed that mitochondria play a critical role in the toxicity of a type B trichothecene. Here, we investigated the direct effects of type A and type B trichothecenes on m...

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Bibliographic Details
Main Authors: Susan McCormick, Nilgun E. Tumer, Debaleena Basu, Mohamed Anwar Bin-Umer, John E. McLaughlin
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:Toxins
Subjects:
trichothecenes
deoxynivalenol
T-2 toxin
diacetoxyscirpenol
Fusarium
mitochondria
ribosomes
translation
fusion
Fission
ROS
Online Access:http://www.mdpi.com/2072-6651/3/12/1484/

Internet

http://www.mdpi.com/2072-6651/3/12/1484/

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