Differential Interaction of Peripheral Blood Lymphocyte Counts (ALC) With Different in vivo Depletion Strategies in Predicting Outcomes of Allogeneic Transplant: An International 2 Center Experience

Differential Interaction of Peripheral Blood Lymphocyte Counts (ALC) With Different in vivo Depletion Strategies in Predicting Outcomes of Allogeneic Transplant: An International 2 Center Experience

Dosing regimens for antithymocyte globulin (ATG) and anti-CD52 antibody (alemtuzumab) for graft vs. host disease prophylaxis (GVHD) are empiric or weight-based, and do not account for individual patient factors. Recently, it has been shown that recipient peripheral blood absolute lymphocyte count (A...

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Bibliographic Details
Main Authors: Vipul Sheth, Vanessa Kennedy, Hugues de Lavallade, Donal Mclornan, Victoria Potter, Brian G. Engelhardt, Bipin Savani, Wichai Chinratanalab, Stacey Goodman, John Greer, Adetola Kassim, Sally York, Michelle Kenyon, Shreyans Gandhi, Austin Kulasekararaj, Judith Marsh, Ghulam Mufti, Antonio Pagliuca, Madan Jagasia, Kavita Raj
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
antithymocyte globulin
alemtuzumab
allogeneic stem cell transplant
acute myeloid leukemia
absolute lymphocyte counts
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00623/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00623/full

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