Essential roles of COUP-TFII in Leydig cell differentiation and male fertility.

Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII; also known as NR2F2), is an orphan nuclear receptor of the steroid/thyroid hormone receptor superfamily. COUP-TFII-null mice die during the early embryonic development due to angiogenesis and cardiovascular defects. To circumven...

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Bibliographic Details
Main Authors: Jun Qin, Ming-Jer Tsai, Sophia Y Tsai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2553269?pdf=render