Circulating microparticles in severe pulmonary arterial hypertension increase intercellular adhesion molecule-1 expression selectively in pulmonary artery endothelium

Circulating microparticles in severe pulmonary arterial hypertension increase intercellular adhesion molecule-1 expression selectively in pulmonary artery endothelium

Abstract Background Microparticles (MPs) stimulate inflammatory adhesion molecule expression in systemic vascular diseases, however it is unknown whether circulating MPs stimulate localized ICAM-1 expression in the heterogeneically distinct pulmonary endothelium during pulmonary arterial hypertensio...

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Bibliographic Details
Main Authors: Leslie A. Blair, April K. Haven, Natalie N. Bauer
Format: Article
Language:English
Published: BMC 2016-10-01
Series:Respiratory Research
Subjects:
Microparticle
Pulmonary hypertension
Inflammation
Endothelium
Online Access:http://link.springer.com/article/10.1186/s12931-016-0445-1

Internet

http://link.springer.com/article/10.1186/s12931-016-0445-1

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