Sequential Molecular and Cellular Events during Neoplastic Progression: A Mouse Syngeneic Ovarian Cancer Model

Sequential Molecular and Cellular Events during Neoplastic Progression: A Mouse Syngeneic Ovarian Cancer Model

Studies performed to identify early events of ovarian cancer and to establish molecular markers to support early detection and development of chemopreventive regimens have been hindered by a lack of adequate cell models. Taking advantage of the spontaneous transformation of mouse ovarian surface ep...

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Bibliographic Details
Main Authors: Paul C. Roberts, Emilio P. Mottillo, Andrea C. Baxa, Henry H.Q. Heng, Nicole Doyon-Reale, Lucie Gregoire, Wayne D. Lancaster, Raja Rabah, Eva M. Schmelz
Format: Article
Language:English
Published: Elsevier 2005-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
E-cadherin
epigenetic silencing
promoter methylation
ovarian cancer
animal model
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605801186

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http://www.sciencedirect.com/science/article/pii/S1476558605801186

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