Insulin-producing cells derived from human embryonic stem cells: comparison of definitive endoderm- and nestin-positive progenitor-based differentiation strategies.

Human embryonic stem cells (hESCs) are pluripotent and capable of undergoing multilineage differentiation into highly specialized cells including pancreatic islet cells. Thus, they represent a novel alternative source for targeted therapies and regenerative medicine for diabetes. Significant progres...

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Bibliographic Details
Main Authors: Rui Wei, Jin Yang, Wenfang Hou, Guoqiang Liu, Meijuan Gao, Lin Zhang, Haining Wang, Genhong Mao, Hongwei Gao, Guian Chen, Tianpei Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23951327/?tool=EBI