CpG methylation controls reactivation of HIV from latency.

CpG methylation controls reactivation of HIV from latency.

DNA methylation of retroviral promoters and enhancers localized in the provirus 5' long terminal repeat (LTR) is considered to be a mechanism of transcriptional suppression that allows retroviruses to evade host immune responses and antiretroviral drugs. However, the role of DNA methylation in...

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Bibliographic Details
Main Authors: Jana Blazkova, Katerina Trejbalova, Françoise Gondois-Rey, Philippe Halfon, Patrick Philibert, Allan Guiguen, Eric Verdin, Daniel Olive, Carine Van Lint, Jiri Hejnar, Ivan Hirsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2722084?pdf=render

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http://europepmc.org/articles/PMC2722084?pdf=render

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