Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers

Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers

Abstract Background/aim Evidence shows that Luminal A breast cancer is likely to undergo bone metastasis, but the mechanisms involved remain unknown. This study’s aim was to demonstrate a correlation between estrogen receptor (ER) positivity and bone metastasis as the clinically preferred site of me...

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Bibliographic Details
Main Authors: Jen-Hwey Chiu, Che-Sheng Wen, Jir-You Wang, Chih-Yi Hsu, Yi-Fang Tsai, Shih-Chieh Hung, Ling-Ming Tseng, Yi-Ming Shyr
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Translational Medicine
Subjects:
Estrogen receptor
Breast cancer
Snail
Bone metastasis
p190 RhoGAP
Online Access:http://link.springer.com/article/10.1186/s12967-017-1192-x

Internet

http://link.springer.com/article/10.1186/s12967-017-1192-x

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