Effects of Changes in the Levels of Damage-Associated Molecular Patterns Following Continuous Veno–Venous Hemofiltration Therapy on Outcomes in Acute Kidney Injury Patients With Sepsis

Effects of Changes in the Levels of Damage-Associated Molecular Patterns Following Continuous Veno–Venous Hemofiltration Therapy on Outcomes in Acute Kidney Injury Patients With Sepsis

Background: We investigated the association of damage-associated molecular pattern (DAMP) removal with mortality in sepsis patients undergoing continuous veno–venous hemofiltration (CVVH).Methods: Circulating levels of DAMPs [mitochondrial DNA (mtDNA); nuclear DNA (nDNA); heat shock protein 70 (HSP7...

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Bibliographic Details
Main Authors: Jie Wu, Jianan Ren, Qinjie Liu, Qiongyuan Hu, Xiuwen Wu, Gefei Wang, Zhiwu Hong, Huajian Ren, Jieshou Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
continuous veno–venous hemofiltration
damage-associated molecular patterns
acute kidney injury
heat shock protein 70
high mobility group box 1
urinary nuclear DNA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03052/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.03052/full

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