Occurrence of long-term depression in the cerebellar flocculus during adaptation of optokinetic response

Long-term depression (LTD) at parallel fiber (PF) to Purkinje cell (PC) synapses has been considered as a main cellular mechanism for motor learning. However, the necessity of LTD for motor learning was challenged by demonstration of normal motor learning in the LTD-defective animals. Here, we addre...

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Bibliographic Details
Main Authors: Takuma Inoshita, Tomoo Hirano
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/36209