Pre-clinical evaluation of a novel nanoemulsion-based hepatitis B mucosal vaccine.

Hepatitis B virus infection remains an important global health concern despite the availability of safe and effective prophylactic vaccines. Limitations to these vaccines include requirement for refrigeration and three immunizations thereby restricting use in the developing world. A new nasal hepati...

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Bibliographic Details
Main Authors: Paul E Makidon, Anna U Bielinska, Shraddha S Nigavekar, Katarzyna W Janczak, Jessica Knowlton, Alison J Scott, Nicholas Mank, Zhengyi Cao, Sivaprakash Rathinavelu, Michael R Beer, J Erby Wilkinson, Luz P Blanco, Jeffrey J Landers, James R Baker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2496893?pdf=render