Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage.

Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage.

Understanding the genetic basis of the physical and behavioral traits that separate humans from other primates is a challenging but intriguing topic. The adaptive functions of the expansion and/or reduction in human brain size have long been explored. From a brain transcriptome project we have ident...

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Bibliographic Details
Main Authors: Huan-Chieh Chien, Hurng-Yi Wang, Yi-Ning Su, Kuan-Yu Lai, Li-Chen Lu, Pau-Chung Chen, Shih-Feng Tsai, Chung-I Wu, Wu-Shiun Hsieh, Che-Kun James Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3468564?pdf=render

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http://europepmc.org/articles/PMC3468564?pdf=render

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