The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice

The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice

Objectives: Glucagon-like peptide-1 (GLP-1) is secreted from enteroendocrine cells and exerts a broad number of metabolic actions through activation of a single GLP-1 receptor (GLP-1R). The cardiovascular actions of GLP-1 have garnered increasing attention as GLP-1R agonists are used to treat human...

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Bibliographic Details
Main Authors: Laurie L. Baggio, John R. Ussher, Brent A. McLean, Xiemin Cao, M. Golam Kabir, Erin E. Mulvihill, Alexandra S. Mighiu, Hangjun Zhang, Andreas Ludwig, Randy J. Seeley, Scott P. Heximer, Daniel J. Drucker
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Molecular Metabolism
Subjects:
GLP-1
Diabetes
Cardiac
Cardiovascular disease
Heart rate
Autonomic nervous system
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817306051

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http://www.sciencedirect.com/science/article/pii/S2212877817306051

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