Modified poloxamer 407 and hyaluronic acid thermosensitive hydrogel-encapsulated keratinocyte growth factor 2 improves knee osteoarthritis in rats

Modified poloxamer 407 and hyaluronic acid thermosensitive hydrogel-encapsulated keratinocyte growth factor 2 improves knee osteoarthritis in rats

Osteoarthritis (OA) is one of the most common chronic diseases, causing degenerative changes in articular cartilage and subchondral bones. To date, there is no effective drug to delay the progression of OA in clinical practice. In this study, we synthesized and prepared a new thermosensitive hydroge...

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Bibliographic Details
Main Authors: Rongshuai Yang, Min Chen, Xuanxin Yang, Wenzhe Sun, Chao Lu, Qi Hui, Changcan Shi, Xiaokun Li, Xiaojie Wang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Materials & Design
Subjects:
Thermosensitive hydrogel
Poloxamer
Hyaluronic acid
Keratinocyte growth factor 2
Safety
Osteoarthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127521006419

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http://www.sciencedirect.com/science/article/pii/S0264127521006419

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