Role of toll-like receptor 7/8 pathways in regulation of interferon response and inflammatory mediators during SARS-CoV2 infection and potential therapeutic options

Role of toll-like receptor 7/8 pathways in regulation of interferon response and inflammatory mediators during SARS-CoV2 infection and potential therapeutic options

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) is the causative agent of Corona Virus Disease 2019 (COVID-19). Lower production of type I and III interferons and higher levels of inflammatory mediators upon SARS-CoV2 infection contribute to COVID-19 pathogenesis. Optimal interferon prod...

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Bibliographic Details
Main Authors: Shetty Ravi Dyavar, Rahul Singh, Rohini Emani, Ganesh P. Pawar, Vinod D. Chaudhari, Anthony T. Podany, Sean N. Avedissian, Courtney V. Fletcher, Deepak B. Salunke
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
SARS-CoV2
COVID-19
TLR7
TLR8
Type I interferons
IL-6
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222100576X

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http://www.sciencedirect.com/science/article/pii/S075333222100576X

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