Serum-Free Culture of Human Mesenchymal Stem Cell Aggregates in Suspension Bioreactors for Tissue Engineering Applications

Mesenchymal stem cells (MSCs) have the capacity to differentiate towards bone, fat, and cartilage lineages. The most widely used culture and differentiation protocols for MSCs are currently limited by their use of serum-containing media and small-scale static culture vessels. Suspension bioreactors...

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Bibliographic Details
Main Authors: Leah M. Allen, John Matyas, Mark Ungrin, David A. Hart, Arindom Sen
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2019/4607461