Activation of CXCL-8 Transcription by Hepatitis E Virus ORF-1 via AP-1

Hepatitis E virus (HEV) is a small nonenveloped single-stranded positive-sense RNA virus and is one of the major causes for acute hepatitis worldwide. CXCL-8 is a small multifunctional proinflammatory chemokine. It was reported recently that HEV infection significantly upregulates CXCL-8 gene expres...

Full description

Bibliographic Details
Main Authors: Zhubing Li, Lu Chen, Qiang Liu
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/495370