Performance of a multiplexed amplicon-based next-generation sequencing assay for HLA typing.

Performance of a multiplexed amplicon-based next-generation sequencing assay for HLA typing.

<h4>Background</h4>Next-generation sequencing (NGS) has enabled efficient high-resolution typing of human leukocyte antigen (HLA) genes with minimal ambiguity. Most commercially available assays amplify individual or subgroup of HLA genes by long-range PCR followed by library preparation...

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Bibliographic Details
Main Authors: Chang Liu, Brian F Duffy, Eric T Weimer, Maureen C Montgomery, Jo-Ellen Jennemann, Rachel Hill, Donna Phelan, Lindsay Lay, Bijal A Parikh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232050

Internet

https://doi.org/10.1371/journal.pone.0232050

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