Development and validation of a High Performance Liquid Chromatographic method for determination of etoposide in biodegradable polymeric implants

Development and validation of a High Performance Liquid Chromatographic method for determination of etoposide in biodegradable polymeric implants

A method using HPLC-UV was developed and validated for the determination of etoposide incorporated into polycaprolactone implants. The method was carried out in isocratic mode using a C18 column (250 x 4.6 mm; 5 µm), at 25 ºC, with acetonitrile and acetic acid 4% (70:30) as mobile phase, a flow rate...

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Bibliographic Details
Main Authors: Ana Gabriela Reis Solano, Gisele Rodrigues da Silva, Silvia Ligório Fialho, Armando da Silva Cunha Júnior, Gérson Antônio Pianetti
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2012-01-01
Series:Química Nova
Subjects:
validation
etoposide
poly(ε-caprolactone)
intraocular implant
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600032&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600032&lng=en&tlng=en

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