Chromatin interactions and expression quantitative trait loci reveal genetic drivers of multimorbidities

Multimorbidities of common diseases often have shared underlying predisposing factors. Here Fadason et al. study the pleiotropy of SNPs and their effects on target genes by integrating chromatin interaction and expression quantitative trait loci data to identify target genes shared between phenotype...

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Bibliographic Details
Main Authors: Tayaza Fadason, William Schierding, Thomas Lumley, Justin M. O’Sullivan
Format: Article
Language:English
Published: Nature Publishing Group 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07692-y