Synthesis, docking study, and in vitro anticancer evaluation of new flufenamic acid derivatives

Novel compounds (6–10) were synthesized and confirmed by spectroscopic analysis, including AT-IR, 1HNMR and CHNS. Their cytotoxic effect was evaluated by MTT assay against two cancer cell lines and two normal cell types. Compound 7 exhibited anticancer activity against MCF-7 breast c...

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Bibliographic Details
Main Authors: Ammar I. Al-Bayati, Ammar A. Razzak Mahmood, Zainab A. Al-Mazaydeh, Majdoleen S. Rammaha, Rheda I. Al-bayati, Fatima Alsoubani, Lubna H. Tahtamouni
Format: Article
Language:English
Published: Pensoft Publishers 2021-05-01
Series:Pharmacia
Online Access:https://pharmacia.pensoft.net/article/66788/download/pdf/