Towards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model

Abstract This paper presents two water-soluble fullerene nanomaterials (HexakisaminoC60 and monoglucosamineC60, which is called here JK39) that were developed and synthesized as non-viral siRNA transfection nanosystems. The developed two-step Bingel–Hirsch reaction enables the chemical modification...

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Bibliographic Details
Main Authors: Julia Korzuch, Monika Rak, Katarzyna Balin, Maciej Zubko, Olga Głowacka, Mateusz Dulski, Robert Musioł, Zbigniew Madeja, Maciej Serda
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89943-5