Scaffold-based 3D cellular models mimicking the heterogeneity of osteosarcoma stem cell niche

Abstract The failure of the osteosarcoma conventional therapies leads to the growing need for novel therapeutic strategies. The lack of specificity for the Cancer Stem Cells (CSCs) population has been recently identified as the main limitation in the current therapies. Moreover, the traditional two-...

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Bibliographic Details
Main Authors: Giada Bassi, Silvia Panseri, Samuele Maria Dozio, Monica Sandri, Elisabetta Campodoni, Massimiliano Dapporto, Simone Sprio, Anna Tampieri, Monica Montesi
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79448-y