Paralog dependency indirectly affects the robustness of human cells
Abstract The protective redundancy of paralogous genes partly relies on the fact that they carry their functions independently. However, a significant fraction of paralogous proteins may form functionally dependent pairs, for instance, through heteromerization. As a consequence, one could expect the...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-09-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.20198871 |