In Silico and In Vitro Analyses of LncRNAs as Potential Regulators in the Transition from the Epithelioid to Sarcomatoid Histotype of Malignant Pleural Mesothelioma (MPM)

In Silico and In Vitro Analyses of LncRNAs as Potential Regulators in the Transition from the Epithelioid to Sarcomatoid Histotype of Malignant Pleural Mesothelioma (MPM)

Malignant pleural mesothelioma (MPM) is a rare malignancy, with extremely poor survival rates. At present, treatment options are limited, with no second line chemotherapy for those who fail first line therapy. Extensive efforts are ongoing in a bid to characterise the underlying molecular mechanisms...

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Bibliographic Details
Main Authors: Anand S. Singh, Richard Heery, Steven G. Gray
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
malignant pleural mesothelioma
long non-coding RNAs (lncRNAs)
epithelial- mesenchymal transition
Online Access:http://www.mdpi.com/1422-0067/19/5/1297

Internet

http://www.mdpi.com/1422-0067/19/5/1297

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