The Study of Pyridazine Compounds on Prostanoids: Inhibitors of COX, cAMP Phosphodiesterase, and TXA2 Synthase

The pyridazine moiety is an important structural feature of various pharmacological active compounds. Synthetic pyridazine compounds have been reported as effective antiprostaglandins (PGs), 5-lipoxygenase (5-LOX), and antiplatelet agents, that is, inhibitors of prostaglandin or cyclooxygenase (COX-...

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Bibliographic Details
Main Author: Mohammad Asif
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2014/703238