Genetic Analysis of Cortical Thickness and Fractional Anisotropy of Water Diffusion in the Brain

Genetic Analysis of Cortical Thickness and Fractional Anisotropy of Water Diffusion in the Brain

ObjectivesThe thickness of the brain’s cortical gray matter (GM) and the fractional anisotropy (FA) of the cerebral white matter (WM) each follow an inverted U-shape trajectory with age. Both measures are positively correlated, suggesting a common biological mechanism. We employed bivariate genetic...

Full description

Bibliographic Details
Main Authors: Peter eKochunov, David eGlahn, Tom eNichols, Anderson eWinkler, Elliott eHong, Henry eHolcomb, Jason eStein, Paul eThompson, Joanne eCurran, Melany eCarless, Rene eOlvera, MP eJohnson, Shelley eCole, Valeria eKochunov, Jack eKent, John eBlangero
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Neuroscience
Subjects:
GWAS
QTL
cortical thickness
imaging genetics
ADAM10
genetic correlation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00120/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00120/full

Similar Items