Myocardial alternative RNA splicing and gene expression profiling in early stage hypoplastic left heart syndrome.

Hypoplastic Left Heart Syndrome (HLHS) is a congenital defect characterized by underdevelopment of the left ventricle and pathological compensation of the right ventricle. If untreated, HLHS is invariably lethal due to the extensive increase in right ventricular workload and eventual failure. Despit...

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Bibliographic Details
Main Authors: Marco Ricci, Yanji Xu, Harriet L Hammond, David A Willoughby, Lubov Nathanson, Maria M Rodriguez, Matteo Vatta, Steven E Lipshultz, Joy Lincoln
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3267718?pdf=render