Preclinical Challenges in Proton Minibeam Radiotherapy: Physics and Biomedical Aspects

Preclinical Challenges in Proton Minibeam Radiotherapy: Physics and Biomedical Aspects

The concept of spatial fractionation in radiotherapy was developed for better sparing of normal tissue in the entrance channel of radiation. Spatial fractionation utilizing proton minibeam radiotherapy (pMBRT) promises to be advantageous compared to X-ray minibeams due to higher dose conformity at t...

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Bibliographic Details
Main Authors: Gerd Datzmann, Matthias Sammer, Stefanie Girst, Michael Mayerhofer, Günther Dollinger, Judith Reindl
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physics
Subjects:
proton minibeam radio therapy
spatial fractionation
linear accelerator
preclinic
irradiation facility
pencil beam scanning
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2020.568206/full

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https://www.frontiersin.org/articles/10.3389/fphy.2020.568206/full

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