Priming Dental Pulp Stem Cells from Human Exfoliated Deciduous Teeth with Fibroblast Growth Factor‐2 Enhances Mineralization Within Tissue‐Engineered Constructs Implanted in Craniofacial Bone Defects

Priming Dental Pulp Stem Cells from Human Exfoliated Deciduous Teeth with Fibroblast Growth Factor‐2 Enhances Mineralization Within Tissue‐Engineered Constructs Implanted in Craniofacial Bone Defects

Abstract The craniofacial area is prone to trauma or pathologies often resulting in large bone damages. One potential treatment option is the grafting of a tissue‐engineered construct seeded with adult mesenchymal stem cells (MSCs). The dental pulp appears as a relevant source of MSCs, as dental pul...

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Bibliographic Details
Main Authors: Anita Novais, Julie Lesieur, Jérémy Sadoine, Lotfi Slimani, Brigitte Baroukh, Bruno Saubaméa, Alain Schmitt, Sibylle Vital, Anne Poliard, Christophe Hélary, Gaël Y. Rochefort, Catherine Chaussain, Caroline Gorin
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Stem Cells Translational Medicine
Subjects:
Bone engineering
Mesenchymal stem cells
Hypoxia
Intramembranous ossification
Calvaria
Online Access:https://doi.org/10.1002/sctm.18-0182

Internet

https://doi.org/10.1002/sctm.18-0182

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