The Coordination of Local Translation, Membranous Organelle Trafficking, and Synaptic Plasticity in Neurons

The Coordination of Local Translation, Membranous Organelle Trafficking, and Synaptic Plasticity in Neurons

Neurons are highly complex polarized cells, displaying an extraordinary degree of spatial compartmentalization. At presynaptic and postsynaptic sites, far from the cell body, local protein synthesis is utilized to continually modify the synaptic proteome, enabling rapid changes in protein production...

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Bibliographic Details
Main Authors: Dipen Rajgor, Theresa M. Welle, Katharine R. Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
local translation
synaptic plasticity
endosomes
lysosomes
neurotransmitter receptors
LTP
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.711446/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.711446/full

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