Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma Cells

<p>Abstract</p> <p>Background</p> <p>Hepatocellular carcinoma (HCC) is the most invasive and frequently diagnosed malignancy and the second leading cause of cancer death in many regions of Asia. The PI3K/Akt/mTOR signal pathway is involved in multiple cellular functions...

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Bibliographic Details
Main Authors: Wu Mengchao, Guo Xianling, Wang Weifeng, Jia Fengqi, Bu Xinxin, Wei Lixin
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/208