A fully orthogonal system for protein synthesis in bacterial cells

Ribosome engineering is an emerging powerful approach for synthetic protein synthesis. Here the authors invert the Ribo-T system, using the engineered ribosome to translate the proteome while the native ribosome translates specific mRNA.

Bibliographic Details
Main Authors: Nikolay A. Aleksashin, Teresa Szal, Anne E. d’Aquino, Michael C. Jewett, Nora Vázquez-Laslop, Alexander S. Mankin
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15756-1