Systemic bacterial infections affect dendritic cell development and function

Systemic bacterial infections affect dendritic cell development and function

Dendritic cells (DCs) are critical in host defense against infection. DC depletion is an early event in the course of sepsis that may impair the host defense mechanisms. Here, we addressed whether DC depletion and dysfunction are pathogen-independent, mediated via pattern recognition receptors, and...

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Bibliographic Details
Main Authors: Kristin Bieber, Manina Günter, Karina A. Pasquevich, Stella E. Autenrieth
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:International Journal of Medical Microbiology
Subjects:
Dendritic cells
Infection
Monocytes
Innate immune defense
TLR
Development
Online Access:http://www.sciencedirect.com/science/article/pii/S1438422121000461

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http://www.sciencedirect.com/science/article/pii/S1438422121000461

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