Long-read based assembly and synteny analysis of a reference Drosophila subobscura genome reveals signatures of structural evolution driven by inversions recombination-suppression effects

Long-read based assembly and synteny analysis of a reference Drosophila subobscura genome reveals signatures of structural evolution driven by inversions recombination-suppression effects

Abstract Background Drosophila subobscura has long been a central model in evolutionary genetics. Presently, its use is hindered by the lack of a reference genome. To bridge this gap, here we used PacBio long-read technology, together with the available wealth of genetic marker information, to assem...

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Bibliographic Details
Main Authors: Charikleia Karageorgiou, Víctor Gámez-Visairas, Rosa Tarrío, Francisco Rodríguez-Trelles
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Genomics
Subjects:
Genome structure evolution
Inversion originating mechanisms
Inversion fixation and polymorphism
Spatiotemporally fluctuating selection
Adaptation
Global change
Online Access:http://link.springer.com/article/10.1186/s12864-019-5590-8

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http://link.springer.com/article/10.1186/s12864-019-5590-8

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