The Endothelial Glycocalyx: New Diagnostic and Therapeutic Approaches in Sepsis

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. The endothelial glycocalyx is one of the earliest sites involved during sepsis. This fragile layer is a complex network of cell-bound proteoglycans, glycosaminoglycan side chains, and sialo...

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Bibliographic Details
Main Authors: Lukas Martin, Patrick Koczera, Elisabeth Zechendorf, Tobias Schuerholz
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/3758278