MiR-378 promoted cell proliferation and inhibited apoptosis by enhanced stem cell properties in chronic myeloid leukemia K562 cells

Dysregulation of miR-378 has been found in diverse types of tumors as well as in leukemia. The role of miR-378 in chronic myeloid leukemia (CML) remains unclear. The aim of the study was to reveal the potential effects of miR-378 in the pathological process and progress in CML. Our results showed ge...

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Bibliographic Details
Main Authors: Jichun Ma, Dehong Wu, Jing Yi, Yunyun Yi, Xin Zhu, Hongchun Qiu, Rong Kong, Jiang Lin, Jun Qian, Zhaoqun Deng
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
CML
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218375735