APOE GENE POLYMORPHISM: THE IMPACT OF APOE4 ALLELE ON SYSTEMIC INFLAMMATION AND ITS ROLE IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE
ApoE is a member of lipoprotein family. It is the most common lipoprotein in the central nervous system (CNS), secreted by astrocytes, microglia, neurons and immunocompetent cells, including lymphocytes, monocytes and macrophages. According to recent data, it has endotheliotropic and immunomodulator...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
SPb RAACI
2018-06-01
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| Series: | Medicinskaâ Immunologiâ |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/1543 |