Nitrate decreases xanthine oxidoreductase-mediated nitrite reductase activity and attenuates vascular and blood pressure responses to nitrite

Nitrite and nitrate restore deficient endogenous nitric oxide (NO) production as they are converted back to NO, and therefore complement the classic enzymatic NO synthesis. Circulating nitrate and nitrite must cross membrane barriers to produce their effects and increased nitrate concentrations may...

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Bibliographic Details
Main Authors: Célio Damacena-Angelis, Gustavo H. Oliveira-Paula, Lucas C. Pinheiro, Eduardo J. Crevelin, Rafael L. Portella, Luiz Alberto B. Moraes, Jose E. Tanus-Santos
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716304219