Erythropoietin Increases Myelination in Oligodendrocytes: Gene Expression Profiling Reveals Early Induction of Genes Involved in Lipid Transport and Metabolism

Erythropoietin Increases Myelination in Oligodendrocytes: Gene Expression Profiling Reveals Early Induction of Genes Involved in Lipid Transport and Metabolism

Several studies have shown that erythropoietin (EPO) has neuroprotective or neuroreparative actions on diseases of the nervous system and that improves oligodendrocyte (OL) differentiation and myelination in vivo and in vitro. This study aims at investigating the early molecular mechanisms for the p...

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Bibliographic Details
Main Authors: Georgina Gyetvai, Trisha Hughes, Florence Wedmore, Cieron Roe, Lamia Heikal, Pietro Ghezzi, Manuela Mengozzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
central glia-4
microarrays
CD36
Pnlip
IGF-1
tissue-protective cytokines
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01394/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01394/full

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