Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology

Gastrointestinal disorders, particularly severe constipation and delayed gastric emptying, are core symptoms of Parkinson's disease that affect most patients. However, the neuropathological substrate and physiological basis for this dysfunction are poorly defined. To begin to explore these phen...

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Bibliographic Details
Main Authors: Robert E. Drolet, Jason R. Cannon, Laura Montero, J. Timothy Greenamyre
Format: Article
Language:English
Published: Elsevier 2009-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109001685