Closing two doors of viral entry: Intramolecular combination of a coreceptor- and fusion inhibitor of HIV-1
<p>Abstract</p> <p>We describe a novel strategy in which two inhibitors of HIV viral entry were incorporated into a single molecule. This bifunctional fusion inhibitor consists of an antibody blocking the binding of HIV to its co-receptor CCR5, and a covalently linked peptide which...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-05-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/5/1/56 |