Disruption of redox homeostasis in liver function and activation of apoptosis on consumption of aspartame in folate deficient rat model

Disruption of redox homeostasis in liver function and activation of apoptosis on consumption of aspartame in folate deficient rat model

This study assesses the effect of long-term intake of aspartame on liver function and apoptosis signaling pathway in the Wistar albino rats. Several reports have suggested that methanol is one of the major metabolites of Aspartame. Non-primate animals are usually resistant to methanol-induced metabo...

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Bibliographic Details
Main Authors: Ashok Iyaswamy, Dapkupar Wankhar, Sundareswaran Loganathan, Sambantham Shanmugam, Ravindran Rajan, Sheeladevi Rathinasamy
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Journal of Nutrition & Intermediary Metabolism
Subjects:
Aspartame
Liver function test
Hepatic injury
Apoptosis
Stress
Free radical
Online Access:http://www.sciencedirect.com/science/article/pii/S2352385916300287

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http://www.sciencedirect.com/science/article/pii/S2352385916300287

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