Peptidomimetic-based antibody surrogate for HER2

Peptidomimetic-based antibody surrogate for HER2

Inhibition of human epidermal growth factor receptor 2 mediated cell signaling pathway is an important therapeutic strategy for HER2-positive cancers. Although monoclonal antibodies are currently used as marketed drugs, their large molecular weight, high cost of production and susceptibility to prot...

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Bibliographic Details
Main Authors: Mengmeng Zheng, Chunpu Li, Mi Zhou, Ru Jia, Fengyu She, Lulu Wei, Feng Cheng, Qi Li, Jianfeng Cai, Yan Wang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Acta Pharmaceutica Sinica B
Subjects:
HER2
Anti-cancer
Peptidomimetics
γ-AApeptides
Antibody-surrogate
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521001556

Internet

http://www.sciencedirect.com/science/article/pii/S2211383521001556

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