Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells

Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells

Objective(s): Cystic fibrosis (CF) is an inherited autosomal recessive disease that is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The present study aimed to investigate the genetic modification of CF with ΔF508 mutation of the CFTR gene using CRISPR i...

Full description

Bibliographic Details
Main Authors: Sepideh Khatibi, Mohammad Reza Modaresi, Reza Kazemi Oskuee, Mohammad Salehi, Hamid Aghaei
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
cftr gene
crispr
cystic fibrosis
peripheral blood mononuclear cells
δf508 mutation
Online Access:https://ijbms.mums.ac.ir/article_17031_41e69d647dcaba0322ebd32eea51c085.pdf

Internet

https://ijbms.mums.ac.ir/article_17031_41e69d647dcaba0322ebd32eea51c085.pdf

Similar Items